Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007667 | 0.73 | NR4A2 (0.53) | KDM4EGLAGAAMETLMNA | |
| SCHEMBL29022514 | 0.72 | KMT2A (0.46) | KDM4EGLAGAAMETLMNA | |
| SCHEMBL3914627 | 0.71 | ALOX5 (0.55) | KDM4EGLAGAAMETLIMK1 | |
| SCHEMBL29576400 | 0.70 | KDM4E (0.58) | KDM4ELMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL68712 | 0.70 | KDM4E (0.58) | KDM4ELMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL17842946 | 0.70 | TSHR (0.43) | KDM4ECHEK1METGSK3BLIMK1 | |
| SCHEMBL29494120 | 0.70 | MAPT (0.52) | KDM4EGLAGAALMNATSHR | |
| SCHEMBL52314 | 0.70 | MAPT (0.52) | KDM4EGLAGAALMNATSHR | |
| SCHEMBL24704203 | 0.69 | NR4A2 (0.54) | KDM4EGLAGAALMNATSHR | |
| SCHEMBL13293021 | 0.69 | TSHR (0.53) | KDM4ELMNATSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2949650-B1 | Synthetic method for the preparation of 1,2-Benzisothiazolin-3-one | SHOUGUANG SYNTECH FINE CHEMICAL CO LTD (CN) | 2017-10-11 | — | — | EP | disclosed |
| US-9334248-B2 | Synthetic method for the preparation of 1, 2-benzisothiazolin-3-one | SHOUGUANG SYNTECH FINE CHEMICAL CO., LTD. (CN) | 2016-05-10 | — | — | US | disclosed |
| EP-2949650-A1 | Synthetic method for the preparation of 1,2-Benzisothiazolin-3-one | Shouguang Syntech Fine Chemical Co., Ltd. (CN) | 2015-12-02 | — | — | EP | disclosed |
| US-20150336910-A1 | SYNTHETIC METHOD FOR THE PREPARATION OF 1, 2-BENZISOTHIAZOLIN-3-ONE | SYNTECH EURO LIMITED (GB) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336910-A1 | SYNTHETIC METHOD FOR THE PREPARATION OF 1, 2-BENZISOTHIAZOLIN-3-ONE | TST, AQP1, BZW1 | KDM4E 3605/4885GLA 3618/4885GAA 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.