SCHEMBL17272811

SCHEMBL17272811

[CH2]CCCCCC(O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.61
FFAR1 O14842 1/20 0.61
TET2 Q6N021 6/20 0.46
KDM4A O75164 2/20 0.46
KDM4C Q9H3R0 2/20 0.46
KDM2A Q9Y2K7 2/20 0.46
TET3 O43151 2/20 0.46
TBXAS1 P24557 2/20 0.43
OR51E2 Q9H255 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
TET1 Q8NFU7 1/20 0.38
MAPT P10636 1/20 0.34
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6678104 1.00 GPR84 (0.61) GPR84FFAR1TET2KDM4AKDM4C
SCHEMBL2733782 1.00 GPR84 (0.61) GPR84FFAR1TET2KDM4AKDM4C
SCHEMBL1227946 1.00 GPR84 (0.61) GPR84FFAR1TET2KDM4AKDM4C
SCHEMBL8923977 0.98 GPR84 (0.58) GPR84FFAR1TET2KDM4AKDM4C
SCHEMBL28788467 0.90
SCHEMBL5696751 0.87 GPR84 (0.76) GPR84FFAR1TET2KDM4AKDM4C
SCHEMBL11651698 0.84 GPR84 (0.71) GPR84FFAR1TET2KDM4AKDM4C
SCHEMBL165661 0.80 TBXAS1 (0.39) GPR84FFAR1TBXAS1MAPTLCK
SCHEMBL27856541 0.80 TBXAS1 (0.39) GPR84FFAR1TBXAS1MAPTLCK
SCHEMBL168355 0.80 TBXAS1 (0.39) GPR84FFAR1TBXAS1MAPTLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150336926-A1 FLUORINATION OF ARYL COMPOUNDS NIH 2015-11-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336926-A1 FLUORINATION OF ARYL COMPOUNDS AFF2, AFF1, AFF4 GPR84 2576/4885FFAR1 342/4885TET2 205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.