Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.48 |
| ▸ | KDM4A | O75164 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.48 |
| ▸ | TET3 | O43151 | 2/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1227946 | 0.98 | GPR84 (0.61) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL17272811 | 0.98 | GPR84 (0.61) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL2733782 | 0.98 | GPR84 (0.61) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL6678104 | 0.98 | GPR84 (0.61) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL28788467 | 0.92 | — | — | |
| SCHEMBL11651698 | 0.87 | GPR84 (0.71) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL5696751 | 0.84 | GPR84 (0.76) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL10697487 | 0.81 | — | — | |
| SCHEMBL11231589 | 0.81 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL167930 | 0.79 | TBXAS1 (0.36) | GPR84FFAR1TBXAS1GSRRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |