Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14492262 | 0.84 | DNM1 (0.52) | DNM1ALDH1A1CYP2D6TAAR1BCHE | |
| SCHEMBL21799963 | 0.82 | ADRB2 (0.40) | ALDH1A1BCHEADRB2 | |
| SCHEMBL14492279 | 0.81 | DNM1 (0.57) | DNM1ALDH1A1CYP2D6TAAR1BCHE | |
| SCHEMBL13995729 | 0.81 | DNM1 (0.50) | DNM1ALDH1A1CYP2D6TAAR1BCHE | |
| SCHEMBL24762812 | 0.80 | MEN1 (0.50) | DNM1ALDH1A1CYP2D6BCHEKDM4E | |
| SCHEMBL12923898 | 0.80 | MEN1 (0.50) | DNM1ALDH1A1CYP2D6BCHEKDM4E | |
| SCHEMBL9737112 | 0.80 | TAAR1 (0.54) | DNM1ALDH1A1CYP2D6TAAR1IDO1 | |
| SCHEMBL5352263 | 0.78 | TAAR1 (0.48) | DNM1ALDH1A1CYP2D6TAAR1IDO1 | |
| SCHEMBL26450919 | 0.76 | DNM1 (0.59) | DNM1ALDH1A1CYP2D6BCHEMMP13 | |
| SCHEMBL4911510 | 0.76 | MEN1 (0.54) | DNM1ALDH1A1CYP2D6TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |