Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 8/20 | 1.00 |
| ▸ | MIF | P14174 | 5/20 | 1.00 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.71 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.71 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.71 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17274428 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL17274357 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL9493211 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL17274466 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| Phenylhexyl Isothiocyanate SCHEMBL7809 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| Phenylbutyl Isothiocyanate SCHEMBL1526828 | 0.98 | MIF (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL1457110 | 0.92 | MIF (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| Phenylhexyl Isothiocyanate SCHEMBL17835311 | 0.90 | NAAA (0.81) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL29126166 | 0.90 | MIF (0.81) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL330501 | 0.88 | MIF (0.81) | NAAAMIFTRPA1CYP2E1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640494-B2 | N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof | NORTHEASTERN UNIVERSITY (US) | 2020-05-05 | — | — | US | disclosed |
| US-10640494-B2 | N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof | NORTHEASTERN UNIVERSITY (US) | 2020-05-05 | — | — | US | disclosed |
| US-20180222894-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Their Use Thereof | NORTHEASTERN UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-20180222894-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Their Use Thereof | NORTHEASTERN UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-20180222894-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Their Use Thereof | NORTHEASTERN UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-9963444-B2 | N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof | NORTHEASTERN UNIVERSITY (US) | 2018-05-08 | — | — | US | disclosed |
| US-9963444-B2 | N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof | NORTHEASTERN UNIVERSITY (US) | 2018-05-08 | — | — | US | disclosed |
| US-9963444-B2 | N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof | NORTHEASTERN UNIVERSITY (US) | 2018-05-08 | — | — | US | disclosed |
| US-20170114050-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Their Use Thereof | NORTHEASTERN UNIVERSITY | 2017-04-27 | — | — | US | disclosed |
| US-20170114050-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Their Use Thereof | NORTHEASTERN UNIVERSITY | 2017-04-27 | — | — | US | disclosed |
| US-20170114050-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Their Use Thereof | NORTHEASTERN UNIVERSITY | 2017-04-27 | — | — | US | disclosed |
| EP-3145505-A1 | N-ACYLETHANOLAMINE HYDROLYZING ACID AMIDASE (NAAA) INHIBITORS AND THEIR USE THEREOF | Northeastern University (US) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015179190-A1 | N-ACYLETHANOLAMINE HYDROLYZING ACID AMIDASE (NAAA) INHIBITORS AND THEIR USE THEREOF | NORTHEASTERN UNIVERSITY (US) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015179190-A1 | N-ACYLETHANOLAMINE HYDROLYZING ACID AMIDASE (NAAA) INHIBITORS AND THEIR USE THEREOF | NORTHEASTERN UNIVERSITY (US) | 2015-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222894-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Their Use Thereof | NAAA, NAT1, NAALAD2 | NAAA 1/4885MIF 3935/4885TRPA1 2207/4885 |
| US-10640494-B2 | N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof | NAAA, NAT1, NAALAD2 | NAAA 1/4885MIF 3935/4885TRPA1 2207/4885 |
| US-20170114050-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Their Use Thereof | NAAA, NAT1, NIT2 | NAAA 1/4885MIF 4260/4885TRPA1 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.