Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 8/20 | 1.00 |
| ▸ | MIF | P14174 | 5/20 | 1.00 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.71 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.71 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.71 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17274428 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL17274357 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL17274355 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL9493211 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL17274466 | 1.00 | NAAA (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| Phenylbutyl Isothiocyanate SCHEMBL1526828 | 0.98 | MIF (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL1457110 | 0.92 | MIF (1.00) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| Phenylhexyl Isothiocyanate SCHEMBL17835311 | 0.90 | NAAA (0.81) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL29126166 | 0.90 | MIF (0.81) | NAAAMIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL330501 | 0.88 | MIF (0.81) | NAAAMIFTRPA1CYP2E1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4424327-A1 | METHOD OR AGENT WITH HDAC REGULATOR, FOR TREATMENT OF DIABETES AND COMPLICATIONS | Biozipcode, Inc. (JP) | 2024-09-04 | — | — | EP | claimed |
| CN-118475370-A | Methods or agents for treating diabetes and complications based on HDAC modulators | 比奥兹普科德公司 | 2024-08-09 | — | — | CN | claimed |
| WO-2023074794-A1 | METHOD OR AGENT WITH HDAC REGULATOR, FOR TREATMENT OF DIABETES AND COMPLICATIONS | 国立大学法人滋賀医科大学 | 2023-05-04 | — | — | WO | claimed |
| CN-104117064-B | Combined application of isothiocyanate compounds and hormone drugs | 无锡杰西医药股份有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-104415332-B | Isosulfocyanate compound and the use in conjunction of kinase inhibitors drug in cancer treatment | 无锡杰西医药科技有限公司 | 2019-05-17 | — | — | CN | claimed |
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (WUXI) COMPANY, INC. (CN) | 2016-09-01 | — | — | US | claimed |
| EP-3034076-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (Wuxi) COMPANY, Inc. (CN) | 2016-06-22 | — | — | EP | claimed |
| CN-104415332-A | Combined application between isothiocyanate-type compound and kinase inhibitor medicine in treatment of cancer | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2015-03-18 | — | — | CN | claimed |
| WO-2010140902-A1 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | HAMPTON MARK (NZ) | 2010-12-09 | — | — | WO | claimed |
| CN-100453076-C | Application of phenhexyl isothiocyanate in preparation of medicament for treating leukemia | XUDONG MA (CN) | 2009-01-21 | — | — | CN | claimed |
| CN-1961873-A | Application of phenhexyl isothiocyanate in preparation of medicament for treating leukemia | MA XUDONG (CN) | 2007-05-16 | — | — | CN | claimed |
| US-5231209-A | Phenylhexyl isothiocyanate | AMERICAN HEALTH FOUNDATION (US) | 1993-07-27 | — | — | US | claimed |
| US-12466789-B2 | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use | THE WILLIAM YARBROUGH FOUNDATION (US) | 2025-11-11 | — | — | US | disclosed |
| US-20250161258-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | THE WILLIAM M YARBROUGH FOUND (US) | 2025-05-22 | — | — | US | disclosed |
| EP-3446689-B1 | ISOTHIOCYANATE COMPOUND FOR USE IN THE TREATMENT OF HYPERBILIRUBINEMIA | JC WUXI COMPANY INC (CN) | 2025-01-08 | — | — | EP | disclosed |
| CN-118873522-A | Application of isothiocyanate compound | 无锡杰西医药股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| US-5231209-A | Phenylhexyl isothiocyanate | AMERICAN HEALTH FOUNDATION (US) | 1993-07-27 | — | — | US | disclosed |
| US-5231209-A | Phenylhexyl isothiocyanate | AMERICAN HEALTH FOUNDATION (US) | 1993-07-27 | — | — | US | disclosed |
| US-5114969-A | Method of inhibiting lung tumors, arylalkyl isothiocyanates, and method of synthesizing same | AMERICAN HEALTH FOUNDATION (US) | 1992-05-19 | — | — | US | disclosed |
| US-5114969-A | Method of inhibiting lung tumors, arylalkyl isothiocyanates, and method of synthesizing same | AMERICAN HEALTH FOUNDATION (US) | 1992-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | CHUK, KIT, MKI67 | NAAA 3936/4885MIF 986/4885TRPA1 2138/4885 |
| US-12466789-B2 | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use | F12, MSR1, TST | NAAA 1667/4885MIF 1902/4885TRPA1 14/4885 |
| US-20250161258-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | TST, TMSB10, NHERF1 | NAAA 1765/4885MIF 2371/4885TRPA1 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.