Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 1.00 |
| ▸ | HTR7 | P34969 | 17/20 | 1.00 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26690390 | 1.00 | HTR1A (1.00) | HTR1AHTR7DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7608424 | 0.87 | HTR1A (0.76) | HTR1AHTR7DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7607604 | 0.85 | HTR1A (0.74) | HTR1AHTR7DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7603494 | 0.85 | HTR1A (0.74) | HTR1AHTR7DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7608421 | 0.85 | HTR1A (0.74) | HTR1AHTR7DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL6542136 | 0.84 | HTR1A (0.72) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL3313069 | 0.76 | CHRM3 (0.77) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL339581 | 0.76 | CHRM3 (0.77) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL3312525 | 0.76 | CHRM3 (0.77) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL7336161 | 0.76 | DRD2 (0.63) | HTR1AHTR7DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145906-B1 | SEROTONIN RECEPTOR-TARGETING COMPOUNDS | UNIV NORTHEASTERN (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3145906-B1 | SEROTONIN RECEPTOR-TARGETING COMPOUNDS | UNIV NORTHEASTERN (US) | 2023-10-04 | — | — | EP | disclosed |
| US-11021435-B2 | Serotonin receptor-targeting compounds and methods | NORTHEASTERN UNIVERSITY (US) | 2021-06-01 | — | — | US | disclosed |
| US-11021435-B2 | Serotonin receptor-targeting compounds and methods | NORTHEASTERN UNIVERSITY (US) | 2021-06-01 | — | — | US | disclosed |
| EP-3145906-A1 | SEROTONIN RECEPTOR-TARGETING COMPOUNDS AND METHODS | Northeastern University (US) | 2017-03-29 | — | — | EP | disclosed |
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-23 | — | — | US | disclosed |
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-23 | — | — | US | disclosed |
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-23 | — | — | US | disclosed |
| WO-2015179366-A1 | SEROTONIN RECEPTOR-TARGETING COMPOUNDS AND METHODS | NORTHEASTERN UNIVERSITY (US) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015179366-A1 | SEROTONIN RECEPTOR-TARGETING COMPOUNDS AND METHODS | NORTHEASTERN UNIVERSITY (US) | 2015-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021435-B2 | Serotonin receptor-targeting compounds and methods | HTR1A, HTR2C, HTR7 | HTR1A 1/4885HTR7 3/4885DRD2 61/4885 |
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | HTR1A, HTR2C, HTR7 | HTR1A 1/4885HTR7 3/4885DRD2 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.