SCHEMBL1727615

SCHEMBL1727615

O=C(Cl)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1727333 0.98 THRB (0.41) THRBCA2CA1MMP1MMP2
SCHEMBL9316060 0.98 THRB (0.41) THRBCA2CA1MMP1MMP2
SCHEMBL1726464 0.92 THRB (0.33) THRBCA2CA1MMP1MMP2
SCHEMBL16941870 0.81 TSHR (0.35) TSHR
SCHEMBL28661533 0.81 TSHR (0.38) TSHR
SCHEMBL26693306 0.78 TET2 (0.34) THRB
SCHEMBL3861185 0.77 THRB (0.44) THRBCA2CA1MMP1MMP2
SCHEMBL8127367 0.76 TDP1 (0.39) THRB
SCHEMBL1727544 0.76 THRB (0.34) THRBTSHR
SCHEMBL3864225 0.75 THRB (0.48) THRBCA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116103021-B Foaming agent for oil-based drilling fluid and preparation method and application thereof 中石化石油工程技术服务有限公司 2024-08-16 CN claimed
CN-114621091-B Surfactant for oil-based foam drilling fluid and preparation method thereof 中石化石油工程技术服务有限公司 2024-07-12 CN claimed
CN-116103024-B Oil-based foaming agent and preparation method thereof 中石化石油工程技术服务有限公司 2024-07-12 CN claimed
CN-116103021-A Foaming agent for oil-based drilling fluid and preparation method and application thereof 中石化石油工程技术服务有限公司 2023-05-12 CN claimed
CN-116103024-A Oil-based foaming agent and preparation method thereof 中石化石油工程技术服务有限公司 2023-05-12 CN claimed
CN-114621110-A Fluorine-containing surfactant for oil-based foam drilling fluid and preparation method thereof 中石化石油工程技术服务有限公司 2022-06-14 CN claimed
CN-114621091-A Surfactant for oil-based foam drilling fluid and preparation method thereof 中石化石油工程技术服务有限公司 2022-06-14 CN claimed
CN-114621110-B Fluorine-containing surfactant for oil-based foam drilling fluid and preparation method thereof 中石化石油工程技术服务有限公司 2025-01-21 CN disclosed
CN-116103021-B Foaming agent for oil-based drilling fluid and preparation method and application thereof 中石化石油工程技术服务有限公司 2024-08-16 CN disclosed
CN-114621091-B Surfactant for oil-based foam drilling fluid and preparation method thereof 中石化石油工程技术服务有限公司 2024-07-12 CN disclosed
CN-116103024-B Oil-based foaming agent and preparation method thereof 中石化石油工程技术服务有限公司 2024-07-12 CN disclosed
CN-116103024-A Oil-based foaming agent and preparation method thereof 中石化石油工程技术服务有限公司 2023-05-12 CN disclosed
CN-116103021-A Foaming agent for oil-based drilling fluid and preparation method and application thereof 中石化石油工程技术服务有限公司 2023-05-12 CN disclosed
EP-2173703-B1 FLUOROALKYL SURFACTANTS DU PONT (US) 2011-11-30 EP disclosed
US-7842626-B2 Partially fluorinated compositions and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-30 US disclosed
EP-2173703-A1 FLUOROALKYL SURFACTANTS E. I. du Pont de Nemours and Company (US) 2010-04-14 EP disclosed
US-7638650-B2 Fluoroalkyl surfactants E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-12-29 US disclosed
WO-2009020910-A1 FLUOROALKYL SURFACTANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-12 WO disclosed
US-20090043130-A1 Fluoroalkyl surfactants E. I. DU PONT DE NEMOURS AND COMPANY 2009-02-12 US disclosed
US-20080113172-A1 Partially fluorinated compositions and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113172-A1 Partially fluorinated compositions and surface active agents FLNB, FLNA, FSCN1 THRB 3891/4885CA2 4039/4885CA1 3299/4885
US-20090043130-A1 Fluoroalkyl surfactants CBR1, CBR3, NHERF1 THRB 3050/4885CA2 2001/4885CA1 3177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.