Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730370 | 0.91 | CNR1 (0.44) | MAPTALDH1A1LMNASMN1; SMN2CNR1 | |
| SCHEMBL1727872 | 0.91 | CASR (0.42) | MAPTALDH1A1LMNASMN1; SMN2CNR1 | |
| SCHEMBL1730286 | 0.90 | CNR1 (0.44) | MAPTALDH1A1LMNASMN1; SMN2CNR1 | |
| SCHEMBL1727718 | 0.88 | CNR1 (0.47) | MAPTCNR1DRD4KMT2ADRD2 | |
| SCHEMBL1728845 | 0.85 | CNR1 (0.45) | CNR1DRD4DRD2CASRPIM1 | |
| SCHEMBL1730213 | 0.85 | DRD4 (0.47) | MAPTLMNASMN1; SMN2HTTDRD4 | |
| SCHEMBL1727691 | 0.84 | CNR1 (0.41) | MAPTALDH1A1LMNACNR1DRD4 | |
| SCHEMBL1729330 | 0.84 | MCHR1 (0.41) | ALDH1A1LMNASMN1; SMN2DRD4MEN1 | |
| SCHEMBL1727866 | 0.82 | CNR1 (0.44) | CNR1DRD4DRD2CASR | |
| SCHEMBL1729806 | 0.80 | CNR1 (0.44) | MAPTALDH1A1LMNASMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |