Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729203 | 0.91 | GRIN1 (0.42) | DRD4PRMT5WDR77DRD3HTR1A | |
| SCHEMBL1729043 | 0.90 | EGLN1 (0.41) | DRD4EGLN1DRD3HTR1AHSD17B10 | |
| SCHEMBL1730270 | 0.90 | EGLN1 (0.47) | DRD4EGLN1PRMT5WDR77DRD3 | |
| SCHEMBL1728914 | 0.86 | MCHR1 (0.44) | DRD4DRD3HTR1AHTR2ASLC6A4 | |
| SCHEMBL1727730 | 0.85 | MAPT (0.46) | DRD4DRD2MAPTTP53AVPR1B | |
| SCHEMBL1728997 | 0.83 | DRD2 (0.42) | DRD4EGLN1DRD3DRD2HTR1A | |
| SCHEMBL1728057 | 0.83 | MCHR1 (0.42) | DRD4DRD3HTR1ALMNASMN1; SMN2 | |
| SCHEMBL1729085 | 0.81 | RET (0.41) | DRD4EGLN1DRD3HTR1AHTR2A | |
| SCHEMBL1728732 | 0.80 | DRD4 (0.62) | DRD4EGLN1DRD3DRD2MAPT | |
| SCHEMBL1730370 | 0.80 | CNR1 (0.44) | DRD4DRD3DRD2HTR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |