Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729330 | 0.92 | MCHR1 (0.41) | CASRACP1DRD2DRD3HTR1A | |
| SCHEMBL1727730 | 0.91 | MAPT (0.46) | CASRDRD2DRD4CNR1PIM1 | |
| SCHEMBL1727992 | 0.89 | CASR (0.41) | CASRIRAK4ACP1DRD2DRD3 | |
| SCHEMBL1729203 | 0.86 | GRIN1 (0.42) | CASRDRD3HTR1ADRD4HTR2A | |
| SCHEMBL1727718 | 0.85 | CNR1 (0.47) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1730370 | 0.84 | CNR1 (0.44) | CASRDRD2DRD3HTR1ADRD4 | |
| SCHEMBL1728845 | 0.83 | CNR1 (0.45) | CASRDRD2DRD3HTR1ADRD4 | |
| SCHEMBL1727691 | 0.82 | CNR1 (0.41) | CASRDRD2DRD3HTR1ADRD4 | |
| SCHEMBL1727394 | 0.81 | HTR1A (0.46) | IRAK4ACP1DRD2DRD3HTR1A | |
| SCHEMBL1728079 | 0.80 | DRD2 (0.42) | CASRACP1DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |