Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729806 | 0.91 | CNR1 (0.44) | CNR1MAPTLMNAALDH1A1HSD17B10 | |
| SCHEMBL1727730 | 0.90 | MAPT (0.46) | CNR1MAPTLMNAALDH1A1HPGD | |
| SCHEMBL1727992 | 0.90 | CASR (0.41) | CNR1DRD4DRD2RAD52PIM1 | |
| SCHEMBL1727643 | 0.86 | CNR1 (0.47) | CNR1MAPTSMN1; SMN2DRD4DRD2 | |
| SCHEMBL1730270 | 0.85 | EGLN1 (0.47) | DRD4DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL1729843 | 0.84 | CNR1 (0.44) | CNR1DRD4DRD2RAD52PIM1 | |
| SCHEMBL1728979 | 0.82 | HTR1A (0.43) | CNR1DRD4DRD2RAD52HTR1A | |
| SCHEMBL1728079 | 0.82 | DRD2 (0.42) | DRD4DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL1727872 | 0.80 | CASR (0.42) | CNR1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1730370 | 0.80 | CNR1 (0.44) | CNR1MAPTLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |