SCHEMBL1727772

SCHEMBL1727772

OCC(O)CC(OCC1CO1)OCC1CO1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 3/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29288354 0.81 ALDH1A1 (0.34) TSHRALDH1A1MAPK1
SCHEMBL13568052 0.81 TSHR (0.39) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL5568873 0.80 TSHR (0.31) TSHR
SCHEMBL2853094 0.78 ALDH1A1 (0.40) TSHRALDH1A1MAPK1
SCHEMBL28020266 0.78 ALDH1A1 (0.30) ALDH1A1
SCHEMBL27993875 0.75
Glycerin SCHEMBL23214508 0.75 TSHR (0.48) TSHRALDH1A1TP53CYP3A4MAPK1
Glycerin SCHEMBL3295078 0.75 TSHR (0.48) TSHRALDH1A1TP53CYP3A4MAPK1
Glycerin SCHEMBL700209 0.75 TSHR (0.48) TSHRALDH1A1TP53CYP3A4MAPK1
Glycerin SCHEMBL42452 0.75 TSHR (0.48) TSHRALDH1A1TP53CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469713-B2 Ampholytic ter-polymers for use in personal care compositions BASF SE (DE) 2016-10-18 US disclosed
WO-2016022161-A1 KERATIN CONDITIONING POLYMERS FOR USE IN PERSONAL CARE COMPOSITONS BASF SE (DE) 2016-02-11 WO disclosed
WO-2015054452-A1 KERATIN CONDITIONING BIO-BASED POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS BASF SE (DE) 2015-04-16 WO disclosed
EP-2403472-B1 AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS BASF SE (DE) 2014-08-20 EP disclosed
US-20140147399-A1 AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS BASF SE (DE) 2014-05-29 US disclosed
US-8663612-B2 Ampholytic ter-polymers for use in personal care compositions BASF SE (DE) 2014-03-04 US disclosed
EP-2234592-B1 PERSONAL CARE COMPOSITIONS COMPRISING CROSSLINKED CATIONIC TERPOLYMERS BASF SE (DE) 2013-06-26 EP disclosed
US-8258248-B2 Preparation of cationic terpolymers and personal care compositions comprising said terpolymers BASF SE (DE) 2012-09-04 US disclosed
EP-2403472-A2 AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS BASF SE (DE) 2012-01-11 EP disclosed
US-7863388-B2 Preparation of functionalized cationic polymers and their application in personal care BASF SE (DE) 2011-01-04 US disclosed
WO-2009115428-A1 CATIONIC POLYMER EMULSIFIERS BASF SE (DE) 2009-09-24 WO disclosed
US-20090175804-A1 Preparation of cationic terpolymers and personal care compositions comprising said terpolymers BASF SE (DE) 2009-07-09 US disclosed
WO-2009080536-A1 PREPARATION OF CATIONIC TERPOLYMERS AND PERSONAL CARE COMPOSITIONS BASF SE (DE) 2009-07-02 WO disclosed
EP-1948700-A2 PREPARATION OF FUNCTIONALIZED CATIONIC POLYMERS AND THEIR PREPARATION AND APPLICATION IN PERSONAL CARE Ciba Holding Inc. (CH) 2008-07-30 EP disclosed
US-20070185281-A1 Preparation of functionalized cationic polymers & their application in personal care BASF SE (DE) 2007-08-09 US disclosed
WO-2007054468-A2 PREPARATION OF FUNCTIONALIZED CATIONIC POLYMERS AND THEIR PREPARATION AND APPLICATION IN PERSONAL CARE CIBA HOLDING INC. (CH) 2007-05-18 WO disclosed
EP-1124862-B1 PREPARATION OF WATER-SOLUBLE CROSS-LINKED CATIONIC POLYMERS CIBA SPEC CHEM WATER TREAT LTD (GB) 2004-10-13 EP disclosed
US-6323306-B1 ADDING TO AQUEOUS SOLUTION OF AN AMINE FUNCTIONALIZED CATIONIC BASE POLYMER CROSS-LINKING AGENT REACTIVE WITH PRIMARY, SECONDARY OR TERTIARY AMINES OF BASE POLYMER TO FORM HIGHER MOLECULAR WEIGHT POLYMER CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) 2001-11-27 US disclosed
EP-1124862-A1 PREPARATION OF WATER-SOLUBLE CROSS-LINKED CATIONIC POLYMERS Ciba Specialty Chemicals Water Treatments Limited (GB) 2001-08-22 EP disclosed
WO-2000014124-A1 PREPARATION OF WATER-SOLUBLE CROSS-LINKED CATIONIC POLYMERS CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090175804-A1 Preparation of cationic terpolymers and personal care compositions comprising said terpolymers CUTA, TERB1, PARG TSHR 2225/4885ALDH1A1 4217/4885TP53 1643/4885
US-20140147399-A1 AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS KRT18, CUTA, PRKDC TSHR 1462/4885ALDH1A1 2601/4885TP53 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.