Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.62 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.62 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTPRA | P18433 | 1/20 | 0.48 |
| ▸ | PTPRB | P23467 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orange G SCHEMBL3020776 | 1.00 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL31621938 | 1.00 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL29388415 | 1.00 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL3873347 | 1.00 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL3020774 | 1.00 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL6051005 | 0.99 | APP (0.69) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| SCHEMBL1098585 | 0.99 | APP (0.69) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL17312267 | 0.99 | APP (0.69) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| SCHEMBL110351 | 0.99 | APP (0.69) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| SCHEMBL461768 | 0.99 | APP (0.69) | APPMAPK1ALDH1A1SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190033319-A1 | BINDING DOMAIN MAPPING | George Mason Research Foundation, Inc. (US) | 2019-01-31 | — | — | US | disclosed |
| US-20150338417-A1 | BINDING DOMAIN MAPPING | GEORGE MASON UNIVERSITY | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190033319-A1 | BINDING DOMAIN MAPPING | SNRPE, HSPBP1, CNBP | APP 3935/4885MAPK1 1907/4885ALDH1A1 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.