Orange G

Orange G

SCHEMBL3020774

O=S(=O)(O)c1cc(S(=O)(=O)O)c2c(/N=N/c3ccccc3)c(O)ccc2c1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.70
▸ MAPK1 P28482 3/20 0.69
▸ ALDH1A1 P00352 1/20 0.69
▸ SUMO2 P61956 1/20 0.62
▸ SUMO1 P63165 1/20 0.62
▸ SENP7 Q9BQF6 1/20 0.62
▸ SENP2 Q9HC62 1/20 0.62
▸ PHLPP2 Q6ZVD8 1/20 0.56
▸ PRMT1 Q99873 1/20 0.54
▸ MAPT P10636 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ GAA P10253 1/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ CYP1A2 P05177 4/20 0.53
▸ CYP2C9 P11712 3/20 0.53
▸ TSHR P16473 1/20 0.48
▸ PTPRA P18433 1/20 0.48
▸ PTPRB P23467 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ HIF1A Q16665 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orange G SCHEMBL3020776 1.00 APP (0.70) APPMAPK1ALDH1A1SUMO2SUMO1
Orange G SCHEMBL31621938 1.00 APP (0.70) APPMAPK1ALDH1A1SUMO2SUMO1
Orange G SCHEMBL29388415 1.00 APP (0.70) APPMAPK1ALDH1A1SUMO2SUMO1
Orange G SCHEMBL3873347 1.00 APP (0.70) APPMAPK1ALDH1A1SUMO2SUMO1
Orange G SCHEMBL17279088 1.00 APP (0.70) APPMAPK1ALDH1A1SUMO2SUMO1
Orange G SCHEMBL6051005 0.99 APP (0.69) APPMAPK1ALDH1A1SUMO2SUMO1
SCHEMBL1098585 0.99 APP (0.69) APPMAPK1ALDH1A1SUMO2SUMO1
Orange G SCHEMBL17312267 0.99 APP (0.69) APPMAPK1ALDH1A1SUMO2SUMO1
SCHEMBL110351 0.99 APP (0.69) APPMAPK1ALDH1A1SUMO2SUMO1
SCHEMBL461768 0.99 APP (0.69) APPMAPK1ALDH1A1SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752201-B1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF UNIV FRIEDRICH ALEXANDER ER (DE) 2023-11-22 — — EP disclosed
US-20230280578-A1 PARAFFIN SHIELD COATING FOR MICROSCOPE SLIDE SHENZHEN PRS LIMITED (CN) 2023-09-07 — — US disclosed
US-11662564-B2 Paraffin shield coating for microscope slide SHENZHEN PRS LIMITED (CN) 2023-05-30 — — US disclosed
EP-3752201-A1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2020-12-23 — — EP disclosed
US-20180155396-A1 STRUCTURE-BASED PEPTIDE INHIBITORS OF P53 AGGREGATION AS A NEW APPROACH TO CANCER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-06-07 — — US disclosed
US-9873718-B2 Structure-based peptide inhibitors of P53 aggregation as a new approach to cancer therapeutics THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-01-23 — — US disclosed
US-20160152648-A1 METAL OXIDE-ORGANIC HYBRID MATERIALS FOR HETEROGENEOUS CATALYSIS AND METHODS OF MAKING AND USING THEREOF YALE UNIVERSITY 2016-06-02 — — US disclosed
US-20160152648-A1 METAL OXIDE-ORGANIC HYBRID MATERIALS FOR HETEROGENEOUS CATALYSIS AND METHODS OF MAKING AND USING THEREOF YALE UNIVERSITY 2016-06-02 — — US disclosed
US-20160068569-A1 STRUCTURE-BASED PEPTIDE INHIBITORS OF P53 AGGREGATION AS A NEW APPROACH TO CANCER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-03-10 — — US disclosed
US-20160068569-A1 STRUCTURE-BASED PEPTIDE INHIBITORS OF P53 AGGREGATION AS A NEW APPROACH TO CANCER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-03-10 — — US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 — — US disclosed
US-20100183480-A1 OZONE DETECTING DEVICE NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2010-07-22 — — US disclosed
US-7754273-B2 Method of printing a time-temperature indicator based on azo coupling reactions onto a susbtrate CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-13 — — US disclosed
EP-2071328-A1 OZONE-DETECTING ELEMENT Nippon Telegraph and Telephone Corporation (JP) 2009-06-17 — — EP disclosed
US-20070218206-A1 Method of Printing a Time-Temperature Indicator Based on Azo Coupling Reactions onto a Susbtrate CIBA SPECIALTY CHEMICALS CORP. 2007-09-20 — — US disclosed
US-7264932-B2 Nuclease inhibitor cocktail APPLERA CORPORATION (US) 2007-09-04 — — US disclosed
US-7264932-B2 Nuclease inhibitor cocktail APPLERA CORPORATION (US) 2007-09-04 — — US disclosed
US-7247483-B2 Method for determining the volume of a liquid sample TECAN TRADING AG (CH) 2007-07-24 — — US disclosed
US-20070032418-A1 Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same AMBION, INC (US) 2007-02-08 — — US disclosed
US-20070032418-A1 Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same AMBION, INC (US) 2007-02-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032418-A1 Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same RNASE1, RNASEH1, RNASEL APP 2583/4885MAPK1 3346/4885ALDH1A1 2603/4885
US-20180155396-A1 STRUCTURE-BASED PEPTIDE INHIBITORS OF P53 AGGREGATION AS A NEW APPROACH TO CANCER THERAPEUTICS TP53, TP53BP1, API5 APP 10/4885MAPK1 2475/4885ALDH1A1 4635/4885
US-20160152648-A1 METAL OXIDE-ORGANIC HYBRID MATERIALS FOR HETEROGENEOUS CATALYSIS AND METHODS OF MAKING AND USING THEREOF SOD1, SOD3, AS3MT APP 4333/4885MAPK1 3361/4885ALDH1A1 2280/4885
US-20160068569-A1 STRUCTURE-BASED PEPTIDE INHIBITORS OF P53 AGGREGATION AS A NEW APPROACH TO CANCER THERAPEUTICS TP53, TP53BP1, API5 APP 10/4885MAPK1 2475/4885ALDH1A1 4635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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