Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.65 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.65 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098585 | 1.00 | APP (0.69) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| SCHEMBL110351 | 1.00 | APP (0.69) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| SCHEMBL7921324 | 0.99 | APP (0.67) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| SCHEMBL10625306 | 0.99 | APP (0.67) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL3020776 | 0.99 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL31621938 | 0.99 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL29388415 | 0.99 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL17279088 | 0.99 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL3020774 | 0.99 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 | |
| Orange G SCHEMBL3873347 | 0.99 | APP (0.70) | APPMAPK1ALDH1A1SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2930126-B1 | Fashionable aerosol dye | HENKEL AG & CO KGAA (DE) | 2019-10-09 | — | — | EP | claimed |
| US-10259946-B1 | Sealing agents, methods of making and uses thereof | James Hardie Technology Limited (IE) | 2019-04-16 | — | — | US | disclosed |
| US-9173829-B2 | Compositions for dyeing keratin fibers | HENKEL AG & CO. KGAA (DE) | 2015-11-03 | — | — | US | disclosed |
| US-9161898-B2 | Compositions for colouring keratin fibres | HENKEL AG & CO. KGAA (DE) | 2015-10-20 | — | — | US | disclosed |
| US-20140298592-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | HENKEL AG & CO. KGAA (DE) | 2014-10-09 | — | — | US | disclosed |
| US-20140290690-A1 | COMPOSITIONS FOR COLOURING KERATIN FIBRES | HENKEL AG & CO. KGAA (DE) | 2014-10-02 | — | — | US | disclosed |
| US-8632612-B2 | Compositions for dyeing keratin fibers | SEGETIS, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| EP-2613760-A2 | COMPOSITIONS FOR DYEING KERATIN FIBERS | Segetis, Inc. (US) | 2013-07-17 | — | — | EP | disclosed |
| US-20130156716-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | SEGETIS, INC. (US) | 2013-06-20 | — | — | US | disclosed |
| EP-2103299-B1 | Oxidizing hair colourant compositions | PROCTER & GAMBLE (US) | 2013-02-27 | — | — | EP | disclosed |
| US-6485529-B1 | Agent and method for coloring fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2002-11-26 | — | — | US | disclosed |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-21 | — | — | US | disclosed |
| US-6461390-B1 | Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| US-6361571-B1 | USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |
| US-6171347-B1 | REMOVAL OF HAIR COLOR TO BE WORN FOR ONLY A SHORT PERIOD OF TIME UNDER MILD, GENTLE CONDITIONS BY USING A COMBINATION OF A SUITABLE REDUCTONE, SUCH AS ASCORBIC ACID, AND/OR A THIOL AND/OR A SULFITE | WELLA AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-6106579-A | MIXTURE OF OXOCARBOXYLIC ACID AND REDUCING AGENT | WELLA AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |
| US-4784959-A | Method of detecting hydrocarbon fuel leaks | LOCKHEED CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| US-4756854-A | Method and apparatus for detecting hydrocarbon fuel leaks | LOCKHEED CORPORATION (US) | 1988-07-12 | — | — | US | disclosed |
| US-4745797-A | Method and apparatus for detecting hydrocarbon fuel leaks | LOCKHEED CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |
| US-4615828-A | Method and apparatus for detecting hydrocarbon fuel leaks | LOCKHEED CORPORATION (US) | 1986-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140290690-A1 | COMPOSITIONS FOR COLOURING KERATIN FIBRES | KRT18, DSG1, PKN1 | APP 2186/4885MAPK1 1485/4885ALDH1A1 2922/4885 |
| US-20140298592-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | KRT18, PKN3, IK | APP 3465/4885MAPK1 2170/4885ALDH1A1 3708/4885 |
| US-20130156716-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | KRT18, KRTCAP2, JUP | APP 1263/4885MAPK1 2748/4885ALDH1A1 1127/4885 |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | ALK, DDC, CBR1 | APP 3901/4885MAPK1 543/4885ALDH1A1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.