Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729365 | 0.87 | NOTUM (0.52) | NOTUMCHRM4POLBLMNAALDH1A1 | |
| SCHEMBL1728028 | 0.83 | NOTUM (0.47) | NOTUMCHRM4POLBLMNAKDM4E | |
| SCHEMBL1727690 | 0.83 | POLB (0.44) | NOTUMPOLBLMNAKDM4EALDH1A1 | |
| SCHEMBL1730124 | 0.77 | CHRM4 (0.46) | CHRM4 | |
| SCHEMBL1727727 | 0.77 | MAP4K4 (0.40) | — | |
| SCHEMBL3265586 | 0.77 | CHRM4 (0.54) | NOTUMCHRM4POLBLMNAKDM4E | |
| SCHEMBL1728683 | 0.76 | DRD3 (0.40) | — | |
| SCHEMBL1727477 | 0.76 | CHRM4 (0.66) | NOTUMCHRM4POLBLMNAKDM4E | |
| SCHEMBL1728139 | 0.75 | CHRM4 (0.39) | NOTUMCHRM4 | |
| SCHEMBL1727922 | 0.75 | DRD2 (0.46) | CHRM4POLBKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |