Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 3/20 | 0.38 |
| ▸ | SKP1 | P63208 | 3/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727727 | 0.91 | MAP4K4 (0.40) | DRD3MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL1727877 | 0.88 | ACACB (0.39) | DRD3HTR1AMAP4K4CKS1BSKP1 | |
| SCHEMBL1728810 | 0.86 | CKS1B (0.38) | PDE10AMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL1727770 | 0.85 | HRH3 (0.38) | DRD3HTR1AMAP4K4CKS1BSKP1 | |
| SCHEMBL1728164 | 0.85 | KDM4E (0.45) | PDE10AMAP4K4HTR3EHTR3BHTR3A | |
| SCHEMBL1727922 | 0.84 | DRD2 (0.46) | DRD3HTR1AHTR2ADRD2 | |
| SCHEMBL1729590 | 0.83 | PTGES (0.46) | DRD3PDE10AMAP4K4CKS1BSKP1 | |
| SCHEMBL1727890 | 0.83 | HTR1A (0.40) | PDE10AHTR1AMAP4K4ACACBACACA | |
| SCHEMBL1727647 | 0.83 | MAP4K4 (0.40) | PDE10AMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL1728883 | 0.82 | MAP4K4 (0.44) | PDE10AMAP4K4CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |