SCHEMBL17279736

SCHEMBL17279736

CC(=O)Oc1ccc(-c2n[nH]c(-c3cccc(-c4nc(-c5ccc(OC(C)=O)cc5)n[nH]4)c3)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.51
▸ GAA P10253 1/20 0.51
▸ ADORA2A P29274 1/20 0.49
▸ ADORA1 P30542 1/20 0.49
▸ NR1H2 P55055 5/20 0.49
▸ NR1H3 Q13133 5/20 0.49
▸ MAPT P10636 2/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ ELANE P08246 1/20 0.45
▸ GRK6 P43250 2/20 0.45
▸ RAB9A P51151 4/20 0.44
▸ NPC1 O15118 3/20 0.44
▸ DGAT1 O75907 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ TSHR P16473 2/20 0.44
▸ NFKB1 P19838 1/20 0.44
▸ NFKB2 Q00653 1/20 0.44
▸ RELA Q04206 1/20 0.44
▸ HPGD P15428 2/20 0.43
▸ POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17279693 0.90 NR1H2 (0.50) LMNAGAANR1H2NR1H3MAPT
SCHEMBL17280107 0.89 NR1H2 (0.59) LMNAGAAADORA2AADORA1NR1H2
SCHEMBL17280075 0.86 NR1H2 (0.56) LMNAGAAADORA2AADORA1NR1H2
SCHEMBL17279738 0.86 NR1H2 (0.56) LMNAADORA2ANR1H2NR1H3MAPT
SCHEMBL22242301 0.83 NR1H2 (0.54) LMNAGAAADORA2AADORA1NR1H2
SCHEMBL17279684 0.81 NR1H2 (0.67) LMNAADORA2AADORA1NR1H2NR1H3
SCHEMBL17280112 0.81 NR1H2 (0.52) LMNAADORA2AADORA1NR1H2NR1H3
SCHEMBL17279765 0.80 NR1H2 (0.54) LMNAADORA2ANR1H2NR1H3MAPT
SCHEMBL17280113 0.79 NR1H2 (0.50) LMNAADORA2AADORA1NR1H2NR1H3
SCHEMBL17280115 0.79 NR1H2 (0.50) LMNAADORA2AADORA1NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020149206-A1 METHOD FOR PRODUCING ACRYLIC RESIN FILM コニカミノルタ株式会社 2020-07-23 — — WO disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-9720140-B2 Optical film, circularly polarizing plate and organic electroluminescent display device Konica Minolta, Inc. (JP) 2017-08-01 — — US disclosed
US-9720140-B2 Optical film, circularly polarizing plate and organic electroluminescent display device Konica Minolta, Inc. (JP) 2017-08-01 — — US disclosed
WO-2017099041-A1 POLYIMIDE FILM, FLEXIBLE PRINTED BOARD, LED LIGHTING DEVICE ETC. コニカミノルタ株式会社 2017-06-15 — — WO disclosed
US-20160070030-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-03-10 — — US disclosed
US-20160070030-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-03-10 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS LMNA 2915/4885GAA 3819/4885ADORA2A 3674/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 LMNA 2773/4885GAA 3895/4885ADORA2A 3985/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 LMNA 3412/4885GAA 4555/4885ADORA2A 3378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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