Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21838011 | 0.90 | CA14 (0.46) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL21838017 | 0.89 | CA14 (0.47) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL136485 | 0.88 | CA14 (0.55) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL133198 | 0.88 | CA14 (0.55) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL1962811 | 0.88 | CA14 (0.55) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL140146 | 0.88 | CA14 (0.55) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL20561267 | 0.88 | CA14 (0.47) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL19032434 | 0.88 | CA14 (0.47) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL15882860 | 0.88 | CA14 (0.47) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL10727968 | 0.87 | CA14 (0.46) | CA14HDAC1HDAC2HDAC6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676818-B2 | Toll-like receptor 2-agonistic lipopeptides, and method of making the same | UNIVERSITY OF KANSAS (US) | 2017-06-13 | — | — | US | disclosed |
| US-20150337009-A1 | TOLL-LIKE RECEPTOR 2-AGONISTIC LIPOPEPTIDES, AND METHOD OF MAKING THE SAME | UNIVERSITY OF KANSAS | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150337009-A1 | TOLL-LIKE RECEPTOR 2-AGONISTIC LIPOPEPTIDES, AND METHOD OF MAKING THE SAME | TLR2, TLR3, TLR1 | CA14 4806/4885HDAC1 4094/4885HDAC2 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.