Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.56 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Neojusticin A SCHEMBL15624855 | 0.95 | MAPT (0.65) | ALDH1A1MAPTKDM4ENPSR1LMNA | |
| Neojusticin A SCHEMBL30637475 | 0.95 | MAPT (0.65) | ALDH1A1MAPTKDM4ENPSR1LMNA | |
| Neojusticin B SCHEMBL30190318 | 0.91 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4ENPSR1LMNA | |
| Neojusticin B SCHEMBL30471811 | 0.91 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4ENPSR1LMNA | |
| Neojusticin B SCHEMBL15920775 | 0.91 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4ENPSR1LMNA | |
| SCHEMBL17280325 | 0.91 | ALDH1A1 (0.69) | ALDH1A1MAPTKDM4ENPSR1LMNA | |
| Taiwanin E Methyl Ether SCHEMBL30637589 | 0.86 | MAPT (0.74) | ALDH1A1MAPTKDM4ENPSR1LMNA | |
| Taiwanin E Methyl Ether SCHEMBL11954034 | 0.86 | MAPT (0.74) | ALDH1A1MAPTKDM4ENPSR1LMNA | |
| SCHEMBL4089401 | 0.85 | TOP2A (0.67) | ALDH1A1MAPTKDM4ENPSR1LMNA | |
| Justicidin A SCHEMBL168356 | 0.82 | ALDH1A1 (0.82) | ALDH1A1MAPTKDM4ENPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650355-B2 | Method for preparation of justicidin a derivatives of arylnaphthalene lignan structure | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-16 | — | — | US | disclosed |
| US-20150336938-A1 | METHOD FOR PREPARATION OF JUSTICIDIN A DERIVATIVES OF ARYLNAPHTHALENE LIGNAN STRUCTURE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336938-A1 | METHOD FOR PREPARATION OF JUSTICIDIN A DERIVATIVES OF ARYLNAPHTHALENE LIGNAN STRUCTURE | UGT1A8, NOTUM, MLN | ALDH1A1 241/4885MAPT 3028/4885KDM4E 3104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.