SCHEMBL17280519

SCHEMBL17280519

COc1cc(N=Nc2cc3c(S(=O)(=O)O)cccc3cc2S(=O)(=O)O)c(C)cc1N=Nc1cc(C)c(N=Nc2cc(C)c(N)cc2C)cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.43
BRD4 O60885 1/20 0.43
CREBBP Q92793 1/20 0.43
SUMO2 P61956 4/20 0.43
SUMO1 P63165 4/20 0.43
SENP7 Q9BQF6 4/20 0.43
SENP2 Q9HC62 4/20 0.43
ATIC P31939 2/20 0.43
ENPP2 Q13822 6/20 0.42
PTPN1 P18031 2/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
APEX1 P27695 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17280514 1.00 TP53 (0.43) TP53BRD4CREBBPSUMO2SUMO1
SCHEMBL17280523 0.93 ENPP2 (0.48) TP53BRD4CREBBPSUMO2SUMO1
SCHEMBL17280504 0.91 SENP2 (0.49) TP53BRD4CREBBPSUMO2SUMO1
SCHEMBL17280515 0.91 SENP2 (0.49) TP53BRD4CREBBPSUMO2SUMO1
SCHEMBL17280507 0.91 SENP2 (0.49) TP53BRD4CREBBPSUMO2SUMO1
SCHEMBL12054251 0.89 ENPP2 (0.44) TP53BRD4CREBBPSUMO2SUMO1
SCHEMBL19958122 0.89 ENPP2 (0.48) TP53BRD4CREBBPSUMO2SUMO1
SCHEMBL17460971 0.87 ENPP2 (0.47) TP53BRD4CREBBPSUMO2SUMO1
SCHEMBL17283957 0.87 ENPP2 (0.47) TP53BRD4CREBBPSUMO2SUMO1
SCHEMBL19958121 0.85 ENPP2 (0.52) TP53BRD4CREBBPSUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9341747-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO LTD (JP) 2016-04-14 US disclosed
US-9244194-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same TYR, CRY1, NAP1L4 TP53 1854/4885BRD4 187/4885CREBBP 2719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.