SCHEMBL17281139

SCHEMBL17281139

CC(C)COc1ccc(-c2c(N)c(N)c(-c3ccc(OCC(C)C)cc3)c3nn(CC(C)C)nc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ XDH P47989 1/20 0.42
▸ KDM4E B2RXH2 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ HPGD P15428 2/20 0.42
▸ MAPT P10636 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.41
▸ LMNA P02545 3/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ TSHR P16473 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15871067 0.93 NPSR1 (0.39) XDHKDM4EALDH1A1HPGDMAPT
SCHEMBL15871087 0.89 LMNA (0.37) XDHKDM4EALDH1A1HPGDMAPT
SCHEMBL15871124 0.83 MAPT (0.39) XDHKDM4EALDH1A1HPGDMAPT
SCHEMBL14799791 0.81 KDM4E (0.44) XDHKDM4EALDH1A1HPGDMAPT
SCHEMBL15871088 0.80 XDH (0.44) XDHKDM4EALDH1A1HPGDMAPT
SCHEMBL17281141 0.80 MEN1 (0.47) XDHKDM4EALDH1A1HPGDMAPT
SCHEMBL15871117 0.79 NPC1 (0.39) XDHKDM4EALDH1A1HPGDMAPT
SCHEMBL15871066 0.75 NPSR1 (0.36) XDHKDM4EALDH1A1HPGDMAPT
SCHEMBL28527296 0.75 MEN1 (0.42) XDHKDM4EALDH1A1HPGDMAPT
SCHEMBL15871070 0.75 MEN1 (0.43) KDM4EALDH1A1HPGDMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840397-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2020-11-17 — — US disclosed
US-10461201-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2019-10-29 — — US disclosed
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 — — US disclosed
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 — — US disclosed
EP-2941474-B1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORP (JP) 2018-02-28 — — EP disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 — — US disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 — — US disclosed
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