Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 4/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 4/20 | 0.33 |
| ▸ | HRH1 | P35367 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18662357 | 0.86 | DGAT1 (0.33) | MAPTDGAT1 | |
| SCHEMBL31305763 | 0.81 | SMN1; SMN2 (0.33) | MAPTDGAT1 | |
| SCHEMBL18681721 | 0.80 | FPR2 (0.37) | KDM4EGLAGAAMAPTHPGD | |
| SCHEMBL6749699 | 0.79 | KDM4E (0.44) | KDM4EPCSK9DGAT1FPR2 | |
| SCHEMBL24189705 | 0.79 | CTSL (0.40) | — | |
| SCHEMBL30396638 | 0.79 | CTSL (0.40) | — | |
| SCHEMBL24509637 | 0.78 | CYP17A1 (0.39) | PCSK9DGAT1FPR2 | |
| SCHEMBL28612046 | 0.75 | NPC1 (0.33) | — | |
| SCHEMBL5661987 | 0.75 | DGAT1 (0.36) | MAPTDGAT1 | |
| SCHEMBL3973414 | 0.74 | SMN1; SMN2 (0.35) | MAPTDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |
| WO-2015179441-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |