SCHEMBL17283250

SCHEMBL17283250

c1ccc2c(c1)Oc1ccccc1N2c1nc2cc3oc(N4c5ccccc5Oc5ccccc54)nc3cc2o1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GABRP O00591 5/20 0.36
▸ GABRD O14764 5/20 0.36
▸ GABRA1 P14867 5/20 0.36
▸ GABRB1 P18505 5/20 0.36
▸ GABRG2 P18507 5/20 0.36
▸ GABRB3 P28472 5/20 0.36
▸ GABRA5 P31644 5/20 0.36
▸ GABRA3 P34903 5/20 0.36
▸ GABRA2 P47869 5/20 0.36
▸ GABRB2 P47870 5/20 0.36
▸ GABRA4 P48169 5/20 0.36
▸ GABRE P78334 5/20 0.36
▸ GABRA6 Q16445 5/20 0.36
▸ GABRG1 Q8N1C3 5/20 0.36
▸ GABRG3 Q99928 5/20 0.36
▸ GABRQ Q9UN88 5/20 0.36
▸ P2RX4 Q99571 5/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ MAPT P10636 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18680432 0.90 MAOA (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17283336 0.89 SMN1; SMN2 (0.52) SMN1; SMN2MAPTKDM4ENPC1POLB
SCHEMBL17283252 0.80 FAAH (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17283248 0.80 KDM4E (0.35) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17283242 0.79 MAOA (0.39) NPSR1
SCHEMBL17283243 0.77 P2RX1 (0.31) P2RX4SMN1; SMN2KDM4ENPC1POLB
SCHEMBL17283259 0.76 CASP3 (0.35) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17283258 0.76 FAAH (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17283238 0.76 NPC1 (0.48) SMN1; SMN2MAPTKDM4ENPC1POLB
SCHEMBL17283249 0.74 HCRTR1 (0.31) SMN1; SMN2KDM4ENPC1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 — — US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 — — US disclosed
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2020-08-13 — — US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 — — US disclosed
WO-2015176981-A1 FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY BASF SE (DE) 2015-11-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 GABRP 4391/4885GABRD 4703/4885GABRA1 3343/4885
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, TEAD2, TEAD4 GABRP 4391/4885GABRD 4703/4885GABRA1 3343/4885
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 GABRP 4391/4885GABRD 4703/4885GABRA1 3343/4885
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 GABRP 4391/4885GABRD 4703/4885GABRA1 3343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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