SCHEMBL17284074

SCHEMBL17284074

COc1cc(N=Nc2cc3c(S(=O)(=O)O)cc(S(=O)(=O)O)cc3cc2S(=O)(=O)O)c(C)cc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 8/20 0.53
▸ SUMO2 P61956 2/20 0.43
▸ SUMO1 P63165 2/20 0.43
▸ SENP7 Q9BQF6 2/20 0.43
▸ SENP3 Q9H4L4 2/20 0.43
▸ SENP2 Q9HC62 2/20 0.43
▸ SENP1 Q9P0U3 2/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ HTT P42858 1/20 0.43
▸ PHLPP2 Q6ZVD8 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ HIF1A Q16665 1/20 0.41
▸ TP53 P04637 2/20 0.40
▸ BRD4 O60885 1/20 0.40
▸ CREBBP Q92793 1/20 0.40
▸ PRMT1 Q99873 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17460971 0.93 ENPP2 (0.47) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL17283957 0.93 ENPP2 (0.47) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL17681937 0.88 SENP2 (0.47) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL17681944 0.88 SENP2 (0.47) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL17681934 0.88 SENP2 (0.47) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL23707752 0.87 ENPP2 (0.65) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL15196108 0.87 ENPP2 (0.65) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL19882688 0.86 ENPP2 (0.60) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL12062856 0.86 ENPP2 (0.49) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL17280523 0.86 ENPP2 (0.48) ENPP2SUMO2SUMO1SENP7SENP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9341747-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 — — US disclosed
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO LTD (JP) 2016-04-14 — — US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same TYR, CRY1, NAP1L4 ENPP2 2889/4885SUMO2 3302/4885SUMO1 1900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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