SCHEMBL17285148

SCHEMBL17285148

c1ccc(-c2ccc3[nH]c4cc(-c5cccc6c5oc5ccccc56)ccc4c3c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.52
GGPS1 O95749 1/20 0.42
PRKDC P78527 2/20 0.42
PTGES2 Q9H7Z7 1/20 0.40
PIM1 P11309 1/20 0.39
CSNK2A2 P19784 1/20 0.39
CSNK2B P67870 1/20 0.39
PIM3 Q86V86 1/20 0.39
PIM2 Q9P1W9 1/20 0.39
CDK4 P11802 2/20 0.38
CCND1 P24385 2/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
TNKS2 Q9H2K2 1/20 0.37
AHR P35869 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788870 0.95 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2PIM1
SCHEMBL788745 0.95 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2PIM1
SCHEMBL26046125 0.95 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2PIM1
SCHEMBL788943 0.94 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2PIM1
SCHEMBL26055682 0.91 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2PIM1
SCHEMBL15790770 0.91 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2PIM1
SCHEMBL26056503 0.90 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PIM1
SCHEMBL788944 0.90 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2PIM1
SCHEMBL17885209 0.90 ALOX5 (0.53) ALOX5GGPS1PRKDCPTGES2PIM1
SCHEMBL787216 0.90 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170317297-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-11-02 US disclosed
WO-2015178732-A1 MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170317297-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME EPCAM, SOD1, ICOSLG ALOX5 2035/4885GGPS1 2365/4885PRKDC 1132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.