Sugi Predict

Sugi Predict / Compounds / SCHEMBL788944

SCHEMBL788944

SCHEMBL788944

c1ccc(-c2ccccc2-c2ccc3[nH]c4ccc(-c5cccc6c5oc5ccccc56)cc4c3c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.57
▸ GGPS1 O95749 1/20 0.46
▸ PRKDC P78527 6/20 0.42
▸ PTGES2 Q9H7Z7 1/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ HPGD P15428 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ BRD4 O60885 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ BRD2 P25440 2/20 0.38
▸ BRD3 Q15059 2/20 0.38
▸ PRMT5 O14744 1/20 0.37
▸ WDR77 Q9BQA1 1/20 0.37
▸ PIM1 P11309 2/20 0.37
▸ CSNK2A2 P19784 2/20 0.37
▸ CSNK2B P67870 2/20 0.37
▸ PIM3 Q86V86 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ CSF1R P07333 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788870 0.95 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL788745 0.95 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL768872 0.94 ALOX5 (0.62) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL788943 0.93 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL18381878 0.93 ALOX5 (0.61) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL30487044 0.92 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2HPGD
SCHEMBL30395989 0.92 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2HPGD
SCHEMBL457912 0.92 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2HPGD
SCHEMBL15790770 0.91 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2HPGD
SCHEMBL18381837 0.90 ALOX5 (0.58) ALOX5GGPS1PRKDCPTGES2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 — — US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 — — US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 — — US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885GGPS1 2063/4885PRKDC 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.