SCHEMBL7764773

SCHEMBL7764773

CN(C)c1cc2c(c(N(C)C)c1)C(c1ccccc1)(c1ccn(C)c1)OC2=O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
HIF1A Q16665 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
RAB9A P51151 1/20 0.37
PTK2B Q14289 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CFTR P13569 1/20 0.35
GOPC Q9HD26 1/20 0.35
LMNA P02545 1/20 0.33
UTS2R Q9UKP6 2/20 0.32
HSP90AA1 P07900 2/20 0.31
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31715255 0.88 ALDH1A1 (0.42) ALDH1A1CYP3A4HPGDHIF1AHSD17B10
SCHEMBL4787644 0.82 ALDH1A1 (0.43) ALDH1A1CYP3A4HPGDHIF1AHSD17B10
SCHEMBL27648758 0.82 TDP1 (0.67) ALDH1A1CYP3A4HPGDHIF1AHSD17B10
SCHEMBL7764771 0.77 ALDH1A1 (0.56) ALDH1A1CYP3A4HPGDHIF1AHSD17B10
SCHEMBL18143537 0.76 ALDH1A1 (0.62) ALDH1A1CYP3A4HPGDHIF1AHSD17B10
SCHEMBL29791059 0.76 ALDH1A1 (0.76) ALDH1A1CYP3A4HPGDHIF1AHSD17B10
SCHEMBL1446856 0.76 ALDH1A1 (0.76) ALDH1A1CYP3A4HPGDHIF1AHSD17B10
SCHEMBL1728542 0.75 MEN1 (0.47) ALDH1A1CYP3A4HPGDHIF1AHSD17B10
SCHEMBL15346931 0.71 ALDH1A1 (0.63) ALDH1A1CYP3A4HPGDHIF1AHSD17B10
SCHEMBL30961234 0.68 ALDH1A1 (0.58) ALDH1A1CYP3A4HPGDHIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405220-A1 HOT MELT WETNESS INDICATOR COMPOSITION THAT INCLUDES A LEUCO DYE, AND ARTICLES INCLUDING THE SAME H.B. Fuller Company (US) 2018-11-28 EP disclosed
WO-2016161329-A1 HOT MELT WETNESS INDICATOR COMPOSITION THAT INCLUDES A LEUCO DYE, AND ARTICLES INCLUDING THE SAME H.B. FULLER COMPANY (US) 2016-10-06 WO disclosed
EP-2890413-A2 A COLOR-CHANGING COMPOSITION AND MATERIAL Kimberly-Clark Worldwide, Inc. (US) 2015-07-08 EP disclosed
EP-2819713-A2 WATER-BASED WETNESS-INDICATING COMPOSITION AND SENSOR Kimberly-Clark Worldwide, Inc. (US) 2015-01-07 EP disclosed
EP-2782537-A1 NON-TACKY WETNESS INDICATOR COMPOSITION FOR APPLICATION ON A POLYMERIC SUBSTRATE Kimberly-Clark Worldwide, Inc. (US) 2014-10-01 EP disclosed
EP-2756295-A2 WETNESS INDICATOR HAVING VARIED HUES Kimberly-Clark Worldwide, Inc. (US) 2014-07-23 EP disclosed
WO-2014033587-A2 A COLOR-CHANGING COMPOSITION AND MATERIAL KIMBERLY-CLARK WORLDWIDE, INC. (US) 2014-03-06 WO disclosed
EP-2658498-A2 ABSORBENT ARTICLE INCLUDING TWO DIMENSIONAL CODE MADE FROM AN ACTIVE GRAPHIC Kimberly-Clark Worldwide, Inc. (US) 2013-11-06 EP disclosed
EP-2654652-A2 ABSORBENT ARTICLES WITH MULTIPLE ACTIVE GRAPHICS Kimberly-Clark Worldwide, Inc. (US) 2013-10-30 EP disclosed
EP-2649149-A2 COLOR-CHANGING COMPOSITION Kimberly-Clark Worldwide, Inc. (US) 2013-10-16 EP disclosed
WO-2000007071-A1 COLOUR CHANGING COMPOSITION AND COLOURING POLYMERIC ARTICLES MADE THEREFROM VANTICO LIMITED (GB) 2000-02-10 WO disclosed
EP-0854783-A1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS ZENECA LIMITED (GB) 1998-07-29 EP disclosed
WO-1997009168-A1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS ZENECA LIMITED (GB) 1997-03-13 WO disclosed
EP-0382523-A2 Heat-sensitive record material NEW OJI PAPER CO., LTD. (JP) 1990-08-16 EP disclosed
EP-0373251-A1 Additive for heat-sensitive recording material, the recording material, and method for production of the recording material SHOWA DENKO KABUSHIKI KAISHA (JP) 1990-06-20 EP disclosed
EP-0358193-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-03-14 EP disclosed
EP-0345755-A2 Heat sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1989-12-13 EP disclosed
EP-0337426-A2 Heat sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1989-10-18 EP disclosed
EP-0326964-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-08-09 EP disclosed
EP-0308978-A2 Multi-color heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-03-29 EP disclosed