SCHEMBL17285602

SCHEMBL17285602

COc1c(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2Op2oc3c(C)cc(C)cc3c3cc(C)cc(C)c3o2)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RARG P13631 1/20 0.30
RXRA P19793 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29326901 0.89 CA1 (0.32)
SCHEMBL18186091 0.88 CA1 (0.33)
SCHEMBL19754902 0.87
SCHEMBL18186086 0.87 RARG (0.33) RARGRXRAPPARG
SCHEMBL16987219 0.86 CA1 (0.35)
SCHEMBL18673560 0.85
SCHEMBL18670913 0.84 CA1 (0.32)
SCHEMBL17126986 0.84 ALDH1A1 (0.30)
SCHEMBL17280440 0.84
SCHEMBL16996690 0.84 CA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3145938-B1 METHOD FOR PRODUCING MONOPHOSPITES EVONIK DEGUSSA GMBH (DE) 2018-12-26 EP disclosed
EP-3088405-B1 NOVEL MONOPHOSPHIT COMPOUNDS WITH A METHYL GROUP EVONIK DEGUSSA GMBH (DE) 2018-11-14 EP disclosed
US-9605010-B2 Monophosphite compounds having a methyl group EVONIK DEGUSSA GMBH (DE) 2017-03-28 US disclosed
US-9605010-B2 Monophosphite compounds having a methyl group EVONIK DEGUSSA GMBH (DE) 2017-03-28 US disclosed
US-9605011-B2 Monophosphite compounds having an ether group EVONIK DEGUSSA GMBH (DE) 2017-03-28 US disclosed
US-9605011-B2 Monophosphite compounds having an ether group EVONIK DEGUSSA GMBH (DE) 2017-03-28 US disclosed
US-9605011-B2 Monophosphite compounds having an ether group EVONIK DEGUSSA GMBH (DE) 2017-03-28 US disclosed
US-9605010-B2 Monophosphite compounds having a methyl group EVONIK DEGUSSA GMBH (DE) 2017-03-28 US disclosed
US-20160318959-A1 NOVEL MONOPHOSPHITE COMPOUNDS HAVING A METHYL GROUP EVONIK DEGUSSA GMBH (DE) 2016-11-03 US disclosed
US-20160318959-A1 NOVEL MONOPHOSPHITE COMPOUNDS HAVING A METHYL GROUP EVONIK DEGUSSA GMBH (DE) 2016-11-03 US disclosed
US-20160318959-A1 NOVEL MONOPHOSPHITE COMPOUNDS HAVING A METHYL GROUP EVONIK DEGUSSA GMBH (DE) 2016-11-03 US disclosed
US-20160318960-A1 NOVEL MONOPHOSPHITE COMPOUNDS HAVING AN ETHER GROUP EVONIK DEGUSSA GMBH (DE) 2016-11-03 US disclosed
US-20160318960-A1 NOVEL MONOPHOSPHITE COMPOUNDS HAVING AN ETHER GROUP EVONIK DEGUSSA GMBH (DE) 2016-11-03 US disclosed
US-20160318960-A1 NOVEL MONOPHOSPHITE COMPOUNDS HAVING AN ETHER GROUP EVONIK DEGUSSA GMBH (DE) 2016-11-03 US disclosed
EP-3088405-A1 NOVEL MONOPHOSPHIT COMPOUNDS WITH A METHYL GROUP Evonik Degussa GmbH (DE) 2016-11-02 EP disclosed
EP-3088406-A1 NOVEL MONOPHOSPHIT COMPOUNDS WITH AN ETHER GROUP Evonik Degussa GmbH (DE) 2016-11-02 EP disclosed
EP-3088405-A1 NOVEL MONOPHOSPHIT COMPOUNDS WITH A METHYL GROUP Evonik Degussa GmbH (DE) 2016-11-02 EP disclosed
EP-3088406-A1 NOVEL MONOPHOSPHIT COMPOUNDS WITH AN ETHER GROUP Evonik Degussa GmbH (DE) 2016-11-02 EP disclosed
WO-2015176928-A1 METHOD FOR PRODUCING MONOPHOSPITES EVONIK DEGUSSA GMBH (DE) 2015-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160318960-A1 NOVEL MONOPHOSPHITE COMPOUNDS HAVING AN ETHER GROUP NUDT1, PHOSPHO1, NUDT14 RARG 1329/4885RXRA 2857/4885PPARG 3573/4885
US-20160318959-A1 NOVEL MONOPHOSPHITE COMPOUNDS HAVING A METHYL GROUP NUDT1, MTAP, MPHOSPH6 RARG 2046/4885RXRA 3968/4885PPARG 4614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.