Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 3/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395459 | 1.00 | GABRR1 (0.64) | GABRR1LMNASLC22A6OR51E2GABBR2 | |
| SCHEMBL16585355 | 0.80 | GABRR1 (0.41) | GABRR1LMNASLC22A6OR51E2 | |
| Gamma-Amino-Beta-Hydroxybutyric Acid SCHEMBL1555143 | 0.78 | — | — | |
| Gamma-Amino-Beta-Hydroxybutyric Acid SCHEMBL10421299 | 0.78 | GABRR1 (1.00) | GABRR1LMNASLC22A6OR51E2GABBR2 | |
| Gamma-Amino-Beta-Hydroxybutyric Acid SCHEMBL2940090 | 0.78 | — | — | |
| Gamma-Amino-Beta-Hydroxybutyric Acid SCHEMBL38621 | 0.78 | — | — | |
| Oxalic Acid SCHEMBL29242433 | 0.77 | GABRR1 (0.60) | GABRR1LMNASLC22A6OR51E2GABBR2 | |
| SCHEMBL13218496 | 0.77 | GABRR1 (0.54) | GABRR1LMNASLC22A6GABBR2GABBR1 | |
| SCHEMBL285410 | 0.77 | CPB2 (0.41) | GABRR1LMNASLC22A6GABBR2GABBR1 | |
| SCHEMBL15819973 | 0.76 | OR51E2 (0.43) | GABRR1LMNASLC22A6OR51E2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150337342-A1 | BIOSYNTHETIC PATHWAYS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2015-11-26 | — | — | US | disclosed |