SCHEMBL285410

SCHEMBL285410

NCCCC(O)CC(=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 3/20 0.41
GPR84 Q9NQS5 4/20 0.39
GSR P00390 1/20 0.39
GABRR1 P24046 3/20 0.38
LMNA P02545 3/20 0.38
RNPEP Q9H4A4 1/20 0.38
THRB P10828 2/20 0.36
BLM P54132 2/20 0.36
KMT2A Q03164 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GABRR3 A8MPY1 1/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
HDAC3 O15379 1/20 0.36
GABBR2 O75899 1/20 0.36
CYP1A2 P05177 1/20 0.36
GABRA1 P14867 1/20 0.36
TSHR P16473 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16585355 0.86 GABRR1 (0.41) CPB2GPR84GSRGABRR1LMNA
SCHEMBL285534 0.82 GABRR1 (0.58) CPB2GPR84GSRGABRR1LMNA
SCHEMBL18163464 0.82 GABRR1 (0.58) CPB2GPR84GSRGABRR1LMNA
SCHEMBL23777965 0.78 GPR84 (0.59) GPR84NFKB1
SCHEMBL395459 0.77 GABRR1 (0.64) GABRR1LMNAGABBR2GABBR1SLC22A6
SCHEMBL17285692 0.77 GABRR1 (0.64) GABRR1LMNAGABBR2GABBR1SLC22A6
SCHEMBL16585311 0.75 THRB (0.43) GPR84GABRR1LMNATHRBSLC22A6
SCHEMBL21566556 0.74 GPR84 (0.64) CPB2GPR84GSRGABRR1LMNA
SCHEMBL23616659 0.73 GPR84 (0.47) GPR84NPSR1TSHRHDAC1HDAC7
SCHEMBL23777972 0.73 GPR84 (0.47) GPR84NPSR1TSHRHDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022727-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA INC (US) 2023-01-26 US claimed
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity GENOMATICA, INC. (US) 2026-03-17 US disclosed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 US disclosed
US-12503711-B2 Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism GENOMATICA, INC. (US) 2025-12-23 US disclosed
US-20250305013-A1 Methods and Compositions for Making Amide Compounds GENOMATICA, INC. (US) 2025-10-02 US disclosed
CN-114728871-B Microorganisms and methods for reducing byproducts 基因组股份公司 2024-12-27 CN disclosed
US-20240294885-A1 ENGINEERED ENZYMES AND METHODS OF MAKING AND USING AGAIN BIO APS (DK) 2024-09-05 US disclosed
EP-4423259-A1 ENGINEERED ENZYMES AND METHODS OF MAKING AND USING Genomatica, Inc. (US) 2024-09-04 EP disclosed
US-11834690-B2 Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid GENOMATICA, INC. (US) 2023-12-05 US disclosed
EP-4277976-A1 METHODS AND COMPOSITIONS FOR MAKING AMIDE COMPOUNDS Genomatica, Inc. (US) 2023-11-22 EP disclosed
US-20170218414-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2017-08-03 US disclosed
US-9458480-B2 Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid GENOMATICA, INC. (US) 2016-10-04 US disclosed
US-8753850-B2 2014-06-17 US disclosed
US-20130303723-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2013-11-14 US disclosed
US-8377680-B2 Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid GENOMATICA, INC. (US) 2013-02-19 US disclosed
WO-2012177721-A1 MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-12-27 WO disclosed
US-20120282661-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-11-08 US disclosed
EP-2427544-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID Genomatica, Inc. (US) 2012-03-14 EP disclosed
US-20100317069-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2010-12-16 US disclosed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity ACADM, ALDH7A1, ADSL CPB2 1449/4885GPR84 3365/4885GSR 1242/4885
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 CPB2 1802/4885GPR84 3361/4885GSR 2365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.