Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17286188 | 0.94 | KDM1A (0.40) | PAOXKDM1ACES2THRBGMNN | |
| SCHEMBL8435869 | 0.84 | — | — | |
| SCHEMBL15282914 | 0.83 | KDM1A (0.47) | KDM1ACES2THRBGMNNTP53 | |
| SCHEMBL14972396 | 0.82 | TSHR (0.54) | KDM1ACES2THRBGMNNTP53 | |
| SCHEMBL10745729 | 0.82 | CES2 (0.62) | KDM1ACES2THRBGMNNTP53 | |
| SCHEMBL10066865 | 0.82 | CES2 (0.62) | KDM1ACES2THRBGMNNTP53 | |
| SCHEMBL9873254 | 0.82 | CES2 (0.62) | KDM1ACES2THRBGMNNTP53 | |
| SCHEMBL4300387 | 0.82 | CES2 (0.62) | KDM1ACES2THRBGMNNTP53 | |
| SCHEMBL9857500 | 0.82 | CES2 (0.62) | KDM1ACES2THRBGMNNTP53 | |
| Hydrochloric Acid SCHEMBL11190904 | 0.82 | KDM4E (0.42) | KDM1ATP53POLBMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183297-A1 | OMEGA-3 ANALOGUES | THE UNIVERSITY OF SYDNEY (AU) | 2017-06-29 | — | — | US | disclosed |
| US-20170183297-A1 | OMEGA-3 ANALOGUES | THE UNIVERSITY OF SYDNEY (AU) | 2017-06-29 | — | — | US | disclosed |
| WO-2015176135-A1 | OMEGA-3 ANALOGUES | THE UNIVERSITY OF SYDNEY (AU) | 2015-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183297-A1 | OMEGA-3 ANALOGUES | ELOVL3, PTGER3, PTGES3 | PAOX 544/4885KDM1A 4791/4885CES2 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.