Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 13/20 | 0.49 |
| ▸ | HTR3A | P46098 | 10/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828936 | 0.82 | HTR4 (0.68) | HTR4HTR3APARP1CHRM1 | |
| SCHEMBL29397140 | 0.82 | HTR4 (0.68) | HTR4HTR3APARP1CHRM1 | |
| SCHEMBL1726614 | 0.77 | HTR4 (0.59) | HTR4HTR3A | |
| SCHEMBL1728218 | 0.77 | HTR4 (0.63) | HTR4HTR3APARP1 | |
| SCHEMBL1727585 | 0.77 | HTR4 (0.59) | HTR4HTR3APARP1 | |
| Trifluoroacetic Acid SCHEMBL829123 | 0.77 | HTR4 (0.61) | HTR4HTR3APARP1CHRM1 | |
| Trifluoroacetic Acid SCHEMBL29399435 | 0.77 | HTR4 (0.61) | HTR4HTR3APARP1CHRM1 | |
| SCHEMBL1728189 | 0.76 | HTR4 (0.59) | HTR4HTR3APARP1 | |
| SCHEMBL1728064 | 0.76 | HTR4 (0.59) | HTR4HTR3A | |
| SCHEMBL828983 | 0.76 | HTR4 (0.82) | HTR4HTR3APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899324-B1 | Benzimidazole-carboxamide compounds as 5-HT4 receptor agonists | THERAVANCE INC (US) | 2011-11-30 | — | — | EP | claimed |