Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.77 |
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | LMNA | P02545 | 7/20 | 0.77 |
| ▸ | HTT | P42858 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 8/20 | 0.73 |
| ▸ | NPC1 | O15118 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002285 | 0.88 | MEN1 (0.68) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL2682054 | 0.88 | KMT2A (1.00) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11007034 | 0.87 | MEN1 (0.79) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11049956 | 0.84 | MEN1 (0.85) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL16566470 | 0.83 | MEN1 (0.77) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL6227015 | 0.83 | MEN1 (0.71) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29533340 | 0.82 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29077780 | 0.82 | MEN1 (0.89) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL10344695 | 0.82 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29556162 | 0.82 | MEN1 (0.89) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9387186-B2 | Thiourea derivatives | CHOUDHARY MUHAMMAD IQBAL (PK) | 2016-07-12 | — | — | US | disclosed |
| US-20150335594-A1 | THIOUREA DERIVATIVES | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335594-A1 | THIOUREA DERIVATIVES | TPMT, TST, NSUN3 | MEN1 3775/4885KMT2A 1755/4885MAPT 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.