Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.68 |
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | NPC1 | O15118 | 9/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | IDH1 | O75874 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17286236 | 0.88 | MEN1 (0.77) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6228295 | 0.86 | KMT2A (0.74) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4548132 | 0.86 | IDH1 (0.64) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4118553 | 0.86 | NPC1 (0.69) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4115751 | 0.85 | NPC1 (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4122903 | 0.84 | NPC1 (0.71) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4105335 | 0.84 | NPC1 (0.64) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4115616 | 0.84 | NPC1 (0.65) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4117928 | 0.83 | NPC1 (0.77) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4112064 | 0.83 | NPC1 (0.62) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054895-A1 | METHODS FOR INDUCING BIOSTASIS IN A CELL, TISSUE OR ORGAN | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-23 | — | — | US | disclosed |
| EP-4087395-A1 | METHODS FOR INDUCING BIOSTASIS IN A CELL, TISSUE OR ORGAN | President And Fellows Of Harvard College (US) | 2022-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054895-A1 | METHODS FOR INDUCING BIOSTASIS IN A CELL, TISSUE OR ORGAN | OPRL1, OPRK1, OPRD1 | MEN1 4386/4885KMT2A 2199/4885MAPT 2778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.