Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17286801 | 1.00 | GRM5 (0.48) | GRM5GRM2MAOAMAOBAKR1C3 | |
| SCHEMBL3327072 | 0.88 | MAOA (0.47) | GRM5MAOAMAOBAKR1C3KDM4E | |
| SCHEMBL15856168 | 0.88 | MAOA (0.47) | GRM5MAOAMAOBAKR1C3KDM4E | |
| SCHEMBL15856197 | 0.88 | MAOA (0.47) | GRM5MAOAMAOBAKR1C3KDM4E | |
| SCHEMBL15856178 | 0.86 | GRM5 (0.46) | GRM5GRM2MAOAMAOBAKR1C3 | |
| SCHEMBL3325784 | 0.86 | GRM5 (0.46) | GRM5GRM2AKR1C3 | |
| SCHEMBL2519025 | 0.86 | GRM5 (0.65) | GRM5GRM2MAOAMAOB | |
| SCHEMBL7304594 | 0.86 | GRM5 (0.65) | GRM5GRM2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL8354006 | 0.85 | GRM5 (0.45) | GRM5GRM2AKR1C3 | |
| SCHEMBL3325285 | 0.82 | ABCB11 (0.48) | GRM5MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416144-B2 | Benzoxazine oxazolidinone compound, preparation method and application thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2016-08-16 | — | — | US | disclosed |
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | OXA1L, XDH, MYD88 | GRM5 889/4885GRM2 3349/4885MAOA 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.