Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073 | 0.86 | KMT2A (0.36) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL1726583 | 0.83 | SMN1; SMN2 (0.39) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL6680 | 0.78 | POLB (0.42) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL715629 | 0.73 | ITGB3 (0.39) | L3MBTL1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL714586 | 0.71 | CYP1A2 (0.38) | KDM4EMAPTITGB3ITGB1ITGAV | |
| SCHEMBL714585 | 0.71 | CYP1A2 (0.38) | KDM4EMAPTITGB3ITGB1ITGAV | |
| SCHEMBL716690 | 0.65 | IDH1 (0.45) | PIK3CD | |
| SCHEMBL17530776 | 0.64 | PIK3CD (0.47) | KMT2APIK3CD | |
| SCHEMBL861347 | 0.64 | PIK3CD (0.41) | KDM4EPOLBGAAMAPTL3MBTL1 | |
| SCHEMBL10751843 | 0.63 | HSP90AA1 (0.63) | KDM4EMEN1POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-A1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma, S.A. (BE) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100405-A1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-09-10 | — | — | WO | disclosed |