Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073 | 0.85 | KMT2A (0.36) | PIK3CDFAAHDRD3BCHEACHE | |
| SCHEMBL1728693 | 0.83 | KDM4E (0.38) | PIK3CDFAAHDRD3BCHEACHE | |
| SCHEMBL6680 | 0.82 | POLB (0.42) | L3MBTL1THRBKDM4EPOLBMEN1 | |
| SCHEMBL716164 | 0.70 | AKT1 (0.40) | PIK3CDL3MBTL1THRBALOX15TSHR | |
| SCHEMBL27781347 | 0.69 | HPGD (0.44) | SMN1; SMN2PIK3CDL3MBTL1KDM4EPOLB | |
| SCHEMBL11318 | 0.69 | TP53 (0.41) | KDM4EMAPTALDH1A1 | |
| SCHEMBL4183076 | 0.67 | HPGD (0.44) | SMN1; SMN2PIK3CDL3MBTL1KDM4EPOLB | |
| SCHEMBL715249 | 0.66 | HPGD (0.43) | SMN1; SMN2PIK3CDL3MBTL1KDM4EPOLB | |
| SCHEMBL28455249 | 0.65 | GAA (0.50) | SMN1; SMN2BCHEACHEL3MBTL1THRB | |
| SCHEMBL10751843 | 0.64 | HSP90AA1 (0.63) | SMN1; SMN2L3MBTL1THRBKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-A1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma, S.A. (BE) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100405-A1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-09-10 | — | — | WO | disclosed |