SCHEMBL1728757

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8128313	0.92	TDP1 (0.60)	ALDH1A1HPGDMAPTKDM4EGAA
	SCHEMBL7015523	0.89	ALDH1A1 (0.55)	ALDH1A1HPGDMAPTKDM4EGAA
	SCHEMBL7423041	0.87	KMT2A (0.58)	ALDH1A1HPGDMAPTKDM4EGAA
	SCHEMBL10761969	0.85	KMT2A (0.55)	ALDH1A1HPGDMAPTKDM4EGAA
	SCHEMBL27806908	0.84	RAB9A (0.52)	ALDH1A1HPGDMAPTKDM4EGAA
	SCHEMBL1484340	0.84	KMT2A (0.54)	ALDH1A1HPGDMAPTKDM4EGAA
	Dimethyl Phthalate SCHEMBL7826081	0.83	KMT2A (0.69)	ALDH1A1HPGDMAPTKDM4EGAA
	SCHEMBL4516565	0.83	KMT2A (0.64)	ALDH1A1HPGDMAPTKDM4EGAA
	SCHEMBL6818034	0.82	ALDH1A1 (0.56)	ALDH1A1HPGDMAPTGAAKMT2A
	SCHEMBL10323667	0.82	TDP1 (0.58)	ALDH1A1HPGDMAPTKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.