Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 4/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728731 | 0.90 | SMYD3 (0.41) | SMYD3HTTKMT2AAKT1CDK2 | |
| SCHEMBL1729837 | 0.74 | SMYD3 (0.42) | SMYD3AKT1CDK2 | |
| SCHEMBL4071612 | 0.69 | SMYD3 (0.60) | SMYD3AKT1CDK2OPRD1 | |
| SCHEMBL1728827 | 0.68 | SMYD3 (0.44) | SMYD3AKT1CDK2SLC6A2SLC6A4 | |
| SCHEMBL1729058 | 0.68 | F11 (0.45) | SMYD3AKT1CDK2SLC6A2 | |
| SCHEMBL1728758 | 0.68 | ADRB1 (0.40) | SMYD3AKT1CDK2 | |
| SCHEMBL3701313 | 0.68 | AKT1 (0.43) | SMYD3AKT1CDK2 | |
| SCHEMBL1727781 | 0.67 | SMYD3 (0.43) | SMYD3AKT1CDK2CPB1 | |
| SCHEMBL1729633 | 0.66 | SMYD3 (0.42) | SMYD3AKT1CDK2 | |
| SCHEMBL27600626 | 0.66 | AKT1 (0.41) | SMYD3AKT1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |