SCHEMBL17288686

SCHEMBL17288686

[CH2]CC(F)(F)CCCCc1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP2C9 P11712 1/20 0.40
MC4R P32245 1/20 0.39
SIGMAR1 Q99720 3/20 0.39
MTNR1A P48039 1/20 0.38
NQO2 P16083 1/20 0.38
CYP2D6 P10635 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
HSP90AB1 P08238 1/20 0.38
MCL1 Q07820 2/20 0.37
TRPV1 Q8NER1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17288611 0.98 SIGMAR1 (0.40) GPR84CYP1A2CYP2C19CYP2C9MC4R
SCHEMBL17288732 0.95 GPR84 (0.41) GPR84CYP1A2CYP2C19CYP2C9MC4R
SCHEMBL17288765 0.89 GPR84 (0.40) GPR84CYP1A2CYP2C19CYP2C9MC4R
SCHEMBL17288488 0.89 CYP1A2 (0.43) CYP1A2CYP2C19CYP2C9MTNR1ANQO2
SCHEMBL17288701 0.84 GPR84 (0.40) GPR84CYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL17288450 0.84 GPR84 (0.40) GPR84CYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL17288595 0.84 BCHE (0.44) GPR84CYP1A2CYP2C19CYP2C9MC4R
SCHEMBL17288437 0.83 CYP1A2 (0.39) GPR84CYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL17288443 0.83 SIGMAR1 (0.44) GPR84CYP1A2CYP2C19CYP2C9MC4R
SCHEMBL17288510 0.83 SIGMAR1 (0.44) GPR84CYP1A2CYP2C19CYP2C9MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 GPR84 2704/4885CYP1A2 193/4885CYP2C19 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.