SCHEMBL17288488

SCHEMBL17288488

[CH2]CC(F)(F)CCc1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2C9 P11712 1/20 0.43
GRM2 Q14416 1/20 0.41
GRM3 Q14832 1/20 0.41
MTNR1A P48039 2/20 0.41
CYP2D6 P10635 1/20 0.41
NQO2 P16083 1/20 0.41
HPGD P15428 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TRPV1 Q8NER1 1/20 0.39
ACP3 P15309 1/20 0.39
SLC18A2 Q05940 1/20 0.38
DAO P14920 1/20 0.38
IDE P14735 1/20 0.38
UBE2N P61088 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17288732 0.90 GPR84 (0.41) CYP1A2CYP2C19CYP2C9MTNR1ACYP2D6
SCHEMBL17288686 0.89 GPR84 (0.40) CYP1A2CYP2C19CYP2C9MTNR1ACYP2D6
SCHEMBL17288458 0.88 CYP1A2 (0.42) CYP1A2CYP2C19CYP2C9GRM2GRM3
SCHEMBL17288611 0.87 SIGMAR1 (0.40) CYP1A2CYP2C19CYP2C9MTNR1ACYP2D6
SCHEMBL17288548 0.85 CYP1A2 (0.40) CYP1A2CYP2C19CYP2C9GRM2GRM3
SCHEMBL17288437 0.84 CYP1A2 (0.39) CYP1A2CYP2C19CYP2C9GRM2GRM3
SCHEMBL28149907 0.83 CYP1A2 (0.44) CYP1A2CYP2C19CYP2C9GRM2GRM3
SCHEMBL17288901 0.82 CYP1A2 (0.47) CYP1A2CYP2C19CYP2C9GRM2GRM3
SCHEMBL17288445 0.82 CYP1A2 (0.46) CYP1A2CYP2C19CYP2C9CYP2D6HPGD
SCHEMBL5255388 0.82 CYP1A2 (0.48) CYP1A2CYP2C19CYP2C9GRM2GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 EP disclosed
US-10251396-B2 Amide compound and use of same for noxious arthropod control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-09 US disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-20170295789-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-19 US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 US disclosed
EP-3178322-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL Sumitomo Chemical Company Limited (JP) 2017-06-14 EP disclosed
EP-3178323-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-06-14 EP disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 CYP1A2 193/4885CYP2C19 1240/4885CYP2C9 343/4885
US-20170295789-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL OPRM1, TRPA1, L3MBTL3 CYP1A2 1172/4885CYP2C19 4244/4885CYP2C9 2616/4885
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND TRPA1, OPRM1, OPRL1 CYP1A2 1038/4885CYP2C19 3864/4885CYP2C9 2203/4885
US-10251396-B2 Amide compound and use of same for noxious arthropod control OPRM1, TRPA1, L3MBTL3 CYP1A2 1172/4885CYP2C19 4244/4885CYP2C9 2616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.