Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16457122 | 0.83 | GRM5 (0.43) | — | |
| SCHEMBL17288705 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1NPC1CYP1A2 | |
| SCHEMBL16879209 | 0.81 | TSHR (0.52) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL17288704 | 0.81 | — | — | |
| SCHEMBL29031247 | 0.75 | CA1 (0.50) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL13471396 | 0.67 | ALDH1A1 (0.33) | APPALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL13471399 | 0.67 | APP (0.35) | APPALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL6364807 | 0.67 | CYP1A2 (0.46) | APPALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL30486188 | 0.65 | TSHR (0.48) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5871989 | 0.65 | APP (0.75) | APPALDH1A1KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1586569-B1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORP (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-7339071-B2 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORPORATION (JP) | 2008-03-04 | — | — | US | disclosed |
| EP-1586569-A1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-20050215820-A1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJI PHOTO FILM CO., LTD. | 2005-09-29 | — | — | US | disclosed |
| US-5725797-A | Silacyclohexane compound, a process for producing the same, and a liquid crystal composition comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |