SCHEMBL17288779

SCHEMBL17288779

COC(c1cc(C(=O)O)no1)C1CCc2ccccc2C1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 3/20 0.37
MTNR1A P48039 4/20 0.36
MTNR1B P49286 4/20 0.36
HPGD P15428 2/20 0.36
AKR1C3 P42330 1/20 0.36
MAPT P10636 2/20 0.35
RECQL P46063 1/20 0.35
FAAH O00519 4/20 0.34
SCD5 Q86SK9 1/20 0.34
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
NPY5R Q15761 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17289094 0.78 NAMPT (0.45)
SCHEMBL17289055 0.78 NPC1 (0.47) SMN1; SMN2ALDH1A1HPGDMAPTRECQL
SCHEMBL7301985 0.72 MTNR1A (0.44) MTNR1AMTNR1BAKR1C3NPY5R
SCHEMBL17288361 0.71 LMNA (0.44) SMN1; SMN2ALDH1A1MAPT
SCHEMBL17288780 0.68 LMNA (0.40) ALDH1A1
SCHEMBL2480890 0.68 MTNR1A (0.47) MTNR1AMTNR1BAKR1C3FAAHIDO1
SCHEMBL19655060 0.67 PLAU (0.44) MTNR1AMTNR1B
SCHEMBL17288956 0.67 KMT2A (0.38) ALDH1A1HPGDMAPTRECQL
SCHEMBL11472821 0.66 MTNR1A (0.45) MTNR1AMTNR1BAKR1C3MAPTFAAH
SCHEMBL3611898 0.65 PLAU (0.46) MTNR1AMTNR1BAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 SMN1; SMN2 2187/4885ALDH1A1 3053/4885MTNR1A 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.