Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480890 | 0.80 | MTNR1A (0.47) | MTNR1AMTNR1BNPY5RPLAUANPEP | |
| SCHEMBL19655060 | 0.79 | PLAU (0.44) | MTNR1AMTNR1BPLAUANPEPKMT2A | |
| SCHEMBL11472821 | 0.78 | MTNR1A (0.45) | MTNR1AMTNR1BPLAUANPEPAKR1C3 | |
| SCHEMBL3611898 | 0.76 | PLAU (0.46) | MTNR1AMTNR1BPLAUANPEPAKR1C3 | |
| SCHEMBL26654656 | 0.76 | MTNR1A (0.44) | MTNR1AMTNR1BNPY5RPLAUANPEP | |
| SCHEMBL17995302 | 0.76 | MTNR1A (0.48) | MTNR1AMTNR1BNPY5RPLAUANPEP | |
| SCHEMBL18984385 | 0.72 | MTNR1A (0.44) | MTNR1AMTNR1BNPY5RPLAUANPEP | |
| SCHEMBL17288779 | 0.72 | SMN1; SMN2 (0.37) | MTNR1AMTNR1BNPY5RAKR1C3 | |
| SCHEMBL2597095 | 0.72 | MTNR1A (0.46) | MTNR1AMTNR1BPLAUANPEPGRM7 | |
| SCHEMBL19688497 | 0.72 | PLAU (0.47) | MTNR1AMTNR1BPLAUANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |