Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727741 | 0.82 | CHRM4 (0.56) | KDM4EGPR119CHRM4THRBALDH1A1 | |
| SCHEMBL3270012 | 0.82 | KDM4E (0.49) | KDM4EPOLBTP53RXFP1GPR119 | |
| SCHEMBL1729244 | 0.81 | CHRM4 (0.40) | CHRM4 | |
| SCHEMBL13622622 | 0.80 | KDM4E (0.57) | KDM4EPOLBTP53L3MBTL1RXFP1 | |
| SCHEMBL1728839 | 0.79 | CHRM4 (0.52) | GPR119MAPTCHRM4ALDH1A1 | |
| SCHEMBL345057 | 0.78 | CHRM4 (0.57) | CHRM4 | |
| SCHEMBL1728730 | 0.78 | MAOA (0.55) | KDM4EGPR119MAPTCHRM4 | |
| SCHEMBL4718806 | 0.77 | BDKRB1 (0.52) | CHRM4 | |
| SCHEMBL1729606 | 0.77 | CHRM4 (0.57) | CHRM4 | |
| SCHEMBL1728821 | 0.77 | CHRM4 (0.68) | KDM4EMAPTCHRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |