Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.40 |
| ▸ | CKS1B | P61024 | 6/20 | 0.40 |
| ▸ | SKP1 | P63208 | 6/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 6/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727776 | 0.89 | CKS1B (0.47) | CKS1BSKP1SKP2FFAR4PIM2 | |
| SCHEMBL3268956 | 0.83 | TPSAB1 (0.41) | CHRM4CKS1BSKP1SKP2FFAR4 | |
| SCHEMBL1728933 | 0.81 | KDM4E (0.54) | CHRM4 | |
| SCHEMBL1728747 | 0.80 | SCD (0.45) | CHRM4 | |
| SCHEMBL2325034 | 0.80 | FFAR4 (0.50) | CHRM4CKS1BSKP1SKP2FFAR4 | |
| SCHEMBL1727946 | 0.78 | HRH4 (0.51) | CHRM4 | |
| SCHEMBL20445981 | 0.78 | HRH3 (0.54) | CHRM4 | |
| SCHEMBL1728004 | 0.77 | HCAR2 (0.53) | CHRM4CKS1BSKP1SKP2 | |
| SCHEMBL1728019 | 0.77 | FFAR4 (0.36) | CKS1BSKP1SKP2FFAR4PIM2 | |
| SCHEMBL1728737 | 0.76 | HSD11B1 (0.49) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |