Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 2/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 8/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729063 | 0.81 | SMYD3 (0.42) | SMYD3AKT1CDK2SLC6A2 | |
| SCHEMBL1729058 | 0.77 | F11 (0.45) | F11SMYD3AKT1CDK2SMO | |
| SCHEMBL3701313 | 0.77 | AKT1 (0.43) | SMYD3AKT1CDK2 | |
| SCHEMBL4071612 | 0.74 | SMYD3 (0.60) | SMYD3AKT1CDK2 | |
| SCHEMBL1728006 | 0.73 | P4HTM (0.37) | SMYD3AKT1CDK2 | |
| SCHEMBL1727688 | 0.72 | SMYD3 (0.43) | SMYD3AKT1CDK2SLC6A2 | |
| SCHEMBL1728827 | 0.70 | SMYD3 (0.44) | SMYD3AKT1CDK2SLC6A2 | |
| SCHEMBL27600626 | 0.70 | AKT1 (0.41) | SMYD3AKT1CDK2 | |
| SCHEMBL13294930 | 0.69 | MIF (0.46) | KMO | |
| SCHEMBL2333984 | 0.68 | AKT1 (0.45) | SMYD3AKT1CDK2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |