Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701313 | 0.75 | AKT1 (0.43) | SMYD3AKT1CDK2 | |
| SCHEMBL1729045 | 0.73 | F11 (0.45) | SMYD3AKT1CDK2 | |
| SCHEMBL18431062 | 0.69 | CYP3A4 (0.48) | CYP1A2CYP3A4CYP2D6ALOX15HSD17B10 | |
| SCHEMBL27600626 | 0.66 | AKT1 (0.41) | SMYD3AKT1CDK2 | |
| SCHEMBL17250004 | 0.66 | CYP3A4 (0.50) | CYP1A2CYP3A4CYP2D6ALOX15HSD17B10 | |
| SCHEMBL25135722 | 0.65 | CD38 (0.49) | CYP2D6CYP2C19SMYD3 | |
| SCHEMBL30363752 | 0.65 | CD38 (0.49) | CYP2D6CYP2C19SMYD3 | |
| SCHEMBL13472422 | 0.65 | CYP1A2 (0.50) | P4HTMCYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL1727781 | 0.65 | SMYD3 (0.43) | SMYD3AKT1CDK2 | |
| SCHEMBL9521235 | 0.65 | CYP3A4 (0.58) | CYP1A2CYP3A4CYP2D6ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |